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In phase I, the enzymatic reactions involve the actions of the enzymes 5-alpha and 5-beta reductases, 3-alpha and 3-beta hydroxysteroid dehydrogenases, and 17-beta hydroxysteroid dehydrogenases. Phase II of nandrolone decanoate metabolism occurs after the conclusion of phase I and involves the conjugation of the phase I metabolites with glucuronic acid or sulfate. The primary breakdown product that arises from the metabolism or nandrolone is 19-norandrosterone. Other breakdown compounds that may also be produced due to the metabolism of nandrolone decanoate include 5-alphadihydronandrolone, 19-norandrosterone, and 19-norethiocholanolone, .

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